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Correction: Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2
Molecular Cancer volume 22, Article number: 115 (2023)
The Original Article was published on 04 February 2020
Correction: Mol Cancer 19, 25 (2020)
Following publication of the original article [1], the authors identified two errors in Fig. 4k (the Transwell image of sh-NC + Vector SOX2 group was misplaced) and Additional file 2: Figure S2a (the EdU image of sh-NC + Vector NC group was misplaced). The corrected Fig. 4k and Figure S2a using the proper images obtained from the original data can be found below.
SOX2OT promotes the stemness phenotype of BCSC by modulating SOX2. a SOX2OT expression level was positively correlated with SOX2 expression level in BC. b Knockdown of SOX2OT decreased SOX2 expression in BCSCs. c The expression of SOX2 and SOX2 target genes were determined using RT-qPCR. d The SOX2 vector significantly reversed the expression level of SOX2 in BCSCs. e and f Overexpressing SOX2 significantly reversed the spheroid-formation ability inhibition induced by silencing SOX2OT. g and h Overexpressing SOX2 significantly reversed the colony forming ability inhibition induced by silencing SOX2OT. i and j Overexpressing SOX2 significantly reversed the cell migration inhibition induced by silencing SOX2OT. k and l Overexpressing SOX2 significantly reversed the cell invasion inhibition induced by silencing SOX2OT
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Zhan Y, Chen Z, He S, et al. Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2. Mol Cancer. 2020;19:25. https://0-doi-org.brum.beds.ac.uk/10.1186/s12943-020-1143-7
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The online version of the original article can be found at https://0-doi-org.brum.beds.ac.uk/10.1186/s12943-020-1143-7.
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Additional file 2: Figure S2
. Overexpressing SOX2 significantly reversed BCSC proliferation inhibition induced by silencing SOX2OT. a and b: Overexpressing SOX2 significantly reversed BCSC proliferation inhibition induced by silencing SOX2OT.
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Zhan, Y., Chen, Z., He, S. et al. Correction: Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2. Mol Cancer 22, 115 (2023). https://0-doi-org.brum.beds.ac.uk/10.1186/s12943-023-01822-x
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DOI: https://0-doi-org.brum.beds.ac.uk/10.1186/s12943-023-01822-x