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Fig. 1 | Molecular Cancer

Fig. 1

From: Evolving insights into the improvement of adoptive T-cell immunotherapy through PD-1/PD-L1 blockade in the clinical spectrum of lung cancer

Fig. 1

The putative origin of lung cancer stem cells in lung anatomical sites. In the trachea and main bronchi, airway basal cells are considered as a stem cell population, precursors of squamous cell lung carcinoma. Pulmonary neuroendocrine (PNE) cells are thought to serve as a precursor for the progress of small cell lung carcinoma. It is also believed that adenocarcinomas can originate from broncho alveolar stem cells or pneumocytes of type I and type II

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