Fig. 1From: Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumorsMMP expression and its clinical relevance in TNBC. a. Gene expression of MMP genes located on MMP region (chr11q22.2) comparing normal (N = 99) and TNBC (N = 90) patient-derived samples from TCGA consortium. Mann-Whitney test. ns: no significant, *P < 0.05, **P < 0.01. b. Correlation matrix for the expression genes located at the MMP locus located genes (P < 0.01). c. Gene distribution at MMP region (top). Genes were classified according to their location as 5’ or 3’. Gene location was used to define MMP signatures to perform Kaplan-Meier curves of relapse-free survival (left) and overall survival (right)Back to article page