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Fig. 25 | Molecular Cancer

Fig. 25

From: Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

Fig. 25

The targeting of tumor vasculature by nanocarriers equipped with ligands. The first image (A) shows the targeting of tumors by cisplatin-loaded polymeric micelles with glucose installed (Gluc-CDDP/m). These micelles use the GLUT1-glucose pathway to enhance their accumulation in tumors and improve their anti-tumor efficacy. The second image (B) demonstrates the GLUT1-mediated vascular translocation of CDDP/m into tumors. Both images (A and B) depict the targeting of tumor vasculature by ligand-installed nanocarriers. Reprint from [34] with a permission from Wiley

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Molecular Cancer

ISSN: 1476-4598