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Table 3 Elaborates the list of ongoing clinical trials on physicochemical combination therapies for the management of skin cancer

From: Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches

NCT Number

Study Title

Phase

Completion of Study

Current state

NCT04977453

GI-101 as a Single Agent or in Combination with Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors

Phase 1

Phase 2

September 2024

Recruiting

NCT05498805

PD-1 Inhibitors with or Without Radiation in Advanced Melanoma

Phase 2

August 15, 2025

Not yet recruiting

NCT03969004

Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients with High-Risk Cutaneous Squamous Cell Carcinoma

Phase 3

February 28, 2027

Recruiting

NCT04879654

Toripalimab Combined with Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery

Phase 2

May 1, 2026

Recruiting

NCT01319565

Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction With 12 Gy Total Body Irradiation (TBI…

Phase 2

June 1, 2025

Active, not recruiting

NCT02806258

Comparing Sequential Neoadjuvant Treatment Including Chemotherapy and Accelerated Radiation Focused to the Tumor Bed vs Neoadjuvant Chemotherapy Alone

Phase 1

Phase 2

December 2025

Recruiting

NCT03025724

Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ

N/A

January 2020

Unknown

NCT05359419

Comparison of Two Modes of Photodynamic Therapy for the Treatment of Actinic Keratosis on the Upper Extremities

Phase 4

December 30, 2023

Not yet recruiting

NCT03110159

DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients

Phase 1

Phase 2

January 2022

Recruiting