Fig. 6
From: Advances in immunotherapy for triple-negative breast cancer
The diagram of bsAb types applied to treat TNBC. F7AK3 with cell surface antigen TROP2 and CD3 facilitates the recruitment of T cells. MesobsFab elicits the recruitment and infiltration of NK cells and leads to the induction of ADCC effect in mesothelin-positive tumors. BiTP was developed for TGF-β and human PD-L1 by using the Check-BODY platform, which increase the collagen deposition, TILs infiltration, CD8 + T cells penetrating