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Table 8 Application of LPHNPs in the treatment of brain tumors

From: Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

Sr. No

Lipid component

Polymer component

Targeting moiety

Drug

In vitro

In vivo

Ref

1

Glyceryl mono stearate, Stearic acid

Chitosan

_

Carbamazepine

_

Wister rats

[286]

2

DSPE-PEG-2000, DPPC, cholesterol

PLGA

cRGD

CRISPR/Cas9

T98G cells

NOD-SCID mice

[291]

3

Lecithin, Soybean phosphatidylcholine,

PLGA

Tocopherol

Rutin (Flavanoid)

_

Swiss mice

[294]