Table 7 Application of LPHNPs for leukemia treatment
Sr. No | Lipid component | Polymer component | Targeting moiety | Drug | In vitro | In vivo | Ref |
|---|---|---|---|---|---|---|---|
1 | Cholesterol, oleic acid | Compritol 888 ATO | Transferrin | PTX | HL-60 | _ | [282] |
2 | DSPE-PEG | PCL | Hyaluronic acid | DOX, and gallic acid | Human K562 chronic myeloid leukemia | AML bearing mice | [283] |
3 | DPPC, DSPE-PEG-2000 | PLGA | Engineered antibody | Tin mesoporphyrin | CD11b + myeloid cells | NOD-SCID il2r gamma − / − (NSG) mice | [284] |