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Table 6 Application of LPHNPs for the treatment of melanoma

From: Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

Sr. No

Lipid component

Polymer component

Targeting moiety

Drug

In vitro

In vivo

Ref

1

DSPE-PEG, HSPC

PLGA

_

DOX

M14 melanoma cells

_

[276]

2

HSPC, Cholesterol, DSPE-PEG-2000

PLGA

Vitamin D

Fluorescein

B16

_

[277]

3

Lecithin, cholesterol

mPEG-PLGA

RGD

CUR

B16

female BALB/c mice

[278]

4

Hydrogenated phosphatidylcholine, DSPE-PEG2K-Maleimide

PLGA

Transferrin

Plumbagin

B16F10

female BALB/c mice

[279]