Table 2 LPHNPs for effective ovarian cancer therapy
Sr. No | Lipid component | Polymer component | Targeting moiety | Drug | In vitro | In vivo | Ref |
|---|---|---|---|---|---|---|---|
1 | Egg phosphatidylcholine, DSPC and DSPE | PLGA | _ | CPT | ES-2 human OC cells | _ | [231] |
2 | Lipoid S75 | Chitosan | _ | CPT and CUR | A2780 cells | _ | [232] |
3 | DSPE-PEG1k-NH2 | PLGA | cRGD | Platinum IV | SKOV3 | Female nude mice | [233] |
4 | Soybean lecithin, DSPE-PEG-2000-COOH, DSPE-PEG-2000-Folate and (1,2-dimyristoyl-sn-glycero3-phosphoethanolamine-diethylene-triamine-pentaacetate | PLGA | Folic acid | PTX and Yittrium-90 | SKOV3 | female Nu/Nu mice | [234] |
5 | DPPC, DPPG and DSPE-PEG (2000)-FA | PLGA | Folic acid | Indocyanine green and perfluoropentane | SKOV3 | _ | [235] |