Fig. 11From: Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeuticsMechanistic illustration of uptake mechanism of cRGD modified Pt (IV) LPHNPs via two distinct mechanisms (a) The prodrugs are actively up taken by passive diffusion and after sonoporation, particles interact favorably with the cell membrane leading to their absorption, (b) through interaction with integrins, particles are taken up via receptor mediated endocytosisBack to article page