Table 2 Univariable and multivariable Cox regression analysis of clinical characteristics and ZEB1 expression
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
ZEB1 | ||||||
 Positive vs Negative | 8.63 | 3.14–23.76 | 0.00003 | 5.82 | 1.82–18.58 | 0.003 |
Age | ||||||
  > 16 years vs ≤ 16 years | 1.23 | 0.53–2.84 | 0.62871 |  |  |  |
Gender | ||||||
 Female vs Male | 0.84 | 0.36–1.96 | 0.67883 |  |  |  |
Relapse | ||||||
 Yes vs No | 4.97 | 2.13–11.61 | 0.00021 | 0.94 | 0.30–2.95 | 0.911 |
Metastasis | ||||||
 Yes vs No | 8.08 | 3.12–20.93 | 0.00002 | 12.05 | 1.28-113.05 | 0.029 |
TNM stage | ||||||
 I vs II/III | 0.19 | 0.08–0.47 | 0.00034 | 2.14 | 0.30-15.47 | 0.045 |
Location | ||||||
 Femur/Tibia vs Else | 0.47 | 0.17–1.29 | 0.14147 | 0.93 | 0.30-2.86 | 0.895 |
Tumor size | ||||||
  > 6 cm vs ≤ 6 cm | 0.53 | 0.22–1.26 | 0.14862 |  0.84 | 0.32-2.21 |  0.722 |