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Fig. 2 | Molecular Cancer

Fig. 2

From: Protein regulator of cytokinesis 1: a potential oncogenic driver

Fig. 2

Association of PRC1 with tumor microenvironment. (A) Correlation of PRC1 with 24 immune cell types in 36 cancers. (B) Extraction of XCELL datasets indicate a significantly positive correlation of PRC1 expression and Th2 cell enrichment in these 36 cancer types. (C) Correlation of PRC1, Th2 cell markers and immune checkpoint genes presented as heatmaps. Statistical significance is shown as *p < 0.05, **p < 0.01, and ***p < 0.001. (D) Survival impact of PRC1 expression in cancers with enhanced or reduced Th2 cell level determined by means of the KM-plotter online tool

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