Fig. 1
From: TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2
TRD translocations and TREC insertions from TRD and TRB loci in T-ALL/T-LBL patients. A Distribution frequency of the TRD partner genes among the 1533 T-ALL/T-LBL patients. ZFP36L2, the new recurrent partner gene, is indicated in light blue. B Schematic representation of insertion of TREC from TRD gene into the ZFP36L2 gene. C Junction sequences of TREC insertion from TRD and TRB loci in ZFP36L2, MORN3, LAMA4, RPP30 and TRG genes. D Fine mapping of chromosome 2 using optical genome mapping indicating an insertion sizing 10 Kb located in ZFP36L2 on 2p21 in UPNs 1044, 1402, 1061, and 1007 and an insertion sizing 1.2 Kb located in ZFP36L2 in UPNS 1309 and LLT-245