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Fig. 7 | Molecular Cancer

Fig. 7

From: Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases

Fig. 7

In vivo immune-stimulation induced by nanoinhibitor. A Representative photographs of abdominal cavity and mesenteries of mice after different treatments. H&E staining and CD3 immunostained images of tumors in different groups. B Schematic illustration of modified PCI score derived from human PCI score. C IFN-γ, TNF-α, and IL-6 concentrations in ascites compared with control group post-treatment. D Modified PCI score of mice individually in different groups. E IFN-γ, TNF-α, and IL-6 concentrations in serum compared with control group post-treatment. F Illustration of proposed antitumor mechanism of the nanoinhibitor. ****p < 0.0001

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