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Table 1 DHA increases microRNA expression levels in MCF7 exosomes

From: Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)

microRNA

Mapped reads

 

Fold-change

P-value

 

Control

DHA

  

miR-23b

205.5

1064.8

5.18

1.0E-20

miR-378

333.3

1510.2

4.53

1.0E-20

let-7f

2949.3

11386.4

3.86

1.0E-20

miR-21

10853.1

41786.2

3.85

1.0E-20

let-7a

4748.9

17764.0

3.74

1.0E-20

miR-182

2044.0

6986.1

3.42

1.0E-20

miR-151-3p

522.1

1760.1

3.37

1.0E-20

miR-27b

4082.4

13189.9

3.23

1.0E-20

let-7e

472.1

1521.1

3.22

1.0E-20

miR-27a

4032.4

12896.6

3.20

1.0E-20

let-7c

449.9

1434.2

3.19

1.1E-16

miR-365

888.7

2824.9

3.18

1.0E-20

miR-320b

516.6

1553.7

3.01

1.0E-20

let-7i

783.2

2335.9

2.98

1.0E-20

miR-30d

955.3

2814.0

2.95

1.0E-20

miR-26a

1122.0

3302.9

2.94

1.0E-20

miR-30a

994.2

2890.0

2.91

1.0E-20

miR-200b

810.9

2314.2

2.85

1.0E-20

miR-181a

399.9

1086.5

2.72

7.5E-11

miR-191

3204.8

7507.6

2.34

1.0E-20

miR-151-5p

938.7

2151.2

2.29

1.0E-20

miR-1246

4537.9

9072.1

2.00

1.0E-20

  1. The microRNAs with a fold-change ≥ 2 and mapped reads ≥1,000 in at least one condition are shown. The fold change was calculated by normalizing the reads to the number of mapped reads and the p-values were calculated using the Likelihood Ratio Test and adjusted using the Benjamini and Hochberg post-test