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Figure 7 | Molecular Cancer

Figure 7

From: Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

Figure 7

EBNA1 inhibits p65 phosphorylation and nuclear translocation in carcinoma cell lines. Western blot analyses of total and phosphorylated (ser 536) p65 in (A) Hone1 cells stably expressing EBNA1 or a neomycin control vector (neo) under basal conditions or following stimulation with IL-1β. Western blotting for EBNA1 and β-actin serve as EBNA1 expression and protein loading controls, respectively. (B) Immunofluorescent staining for p65 in Ad/AH cells stably expressing EBNA1 or a neomycin control vector (neo) under basal conditions or following stimulation with 100 ng/ml TNFα.

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Molecular Cancer

ISSN: 1476-4598