Figure 1From: Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survivalAur-A is overexpressed in TSCC tissues and correlated with clinical stage and lymph node metastasis. TSCC or its corresponding adjacent normal samples were collected and subjected to immunohistochemical staining with Aur-A antibody. (a) Aur-A expression is low in normal samples. (b) Aur-A expression is obviously increased in TSCC, original magnification, × 200. Insets show enlarged views, original magnification, × 400.Back to article page