Figure 5From: Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasivenessAnti-CK MAb changes the morphology of MCF-10A neoT cells cultured on fibronectin. Photomicrographs of MCF-10A neoT cells cultured for 24 h on uncoated (below) or fibronectin-coated surfaces (above) are shown for control and anti-CK8 MAb treated cells. Anti-CK MAb enables the adhesion to fibronectin of MCF-10A neoT cells, but not control cells, which form cell clusters. In contrast, both control and anti-CK MAb treated cells adhere to uncoated surface.Back to article page