Figure 6From: An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animalsMI-319 induces cell apoptosis in FSCCL cells only. (A) Cells were stained with Annexin V-FITC and quantification of the percentage of apoptotic cells was done with a Coulter EPICS 753 flow cytometer. (B) Tunnel assay. TdT+ cells (apoptotic cells) were assessed with a Coulter EPICS 753 flow cytometer. Numbers plotted here are the average of three independent experiments. * represents p < 0.05 and ** represents p < 0.01.Back to article page