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Figure 4 | Molecular Cancer

Figure 4

From: Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis

Figure 4

Analysis of protocol 2 genes increased in the BALBLps-d tumors compared to BALB tumors. Supervised and unsupervised bioinformatic methods were used for these analyses. A. Cluster 4 identified using statistical (Genespring) analysis. Each vertical line represents one sample for each strain for an n = 2 (Un = uninvolved, MCA = 3-methlycholanthrene, and for BALBLps-dtumor) with the exception of BALB tumor (n = 1), indicated by the small horizontal black line above each treatment on the x-axis. B. Profile (Spotfire) analysis similar to that of cluster 4. Z-score (y-axis) is the intensity in terms of standard deviations (SD) from the mean. The z-score is calculated by subtracting the mean and dividing by the SD for each probeset. See Additional file 6, Figure S3 for supervised and unsupervised analysis depicted as heat maps.

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Molecular Cancer

ISSN: 1476-4598