From: Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling
Treatment | Experiment | Experiment 1-5 | |||||
---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | |||
DMSO | 1.06 | 0.91 | 0.96 | Â | Â | ||
ut | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | ||
2 h | TQ | 0.90 | 0.87 | 0.66 | 0.47 | Â | |
PI3K-inh. | 0.69 | 0.84 | 0.86 | 0.57 | |||
[1] TQ + PI3K-inh. | 0.61 | 0.47 | 0.46 | 0.41 | Â | ||
[2] Multiplication of TQxPI3K-Inh. | 0.61 | 0.73 | 0.56 | 0.27 | Â | ||
−0.01 | −0.26 | −0.10 | 0.15 |  | −0.06 (±0.17)* | ||
4 h | TQ | 0.93 | 1.07 | 0.76 | Â | 0.92 | Â |
PI3K inh. | 0.67 | 1.04 | 0.64 | 0.69 | |||
[1] TQ + PI3K inh. | 0.59 | 0.53 | 0.47 | 0.62 | |||
[2] Multiplication of TQxPI3K-Inh. | 0.62 | 1.11 | 0.49 | 0.63 | |||
−0.03 | −0.59 | −0.02 |  | −0.01 | −0.16 (±0.28)** |