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Table 3 TIMP-4 expression in human cancer.

From: Tissue Inhibitor of Metalloproteinases-4. The road less traveled

Cancer

Assay

Expression

Reference

Breast

IHC

↑ in early stages, ↓ in advanced stages

[54]

Ovary

IHC

↑

[78]

Cervical

RT-PCR

↑

[77]

Prostate

IHC

↑ in early stages, ↓ in advanced stages

[83]

Gliomas

RT-PCR

↑ in early stages, ↓ in advanced stages

[76]

Pancreas

IHC

↓

[75]

Colon

IHC

↑

[80]

Endometrium

IHC

↑

[46, 53]

Kidney Papillary

RT-PCR

↑

[81]

Kidney Clear cell

RT-PCR

↓

[81]

  1. Published research.
  2. Up and down arrows represent increased and decreased expression, respectively