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Table 1 Sequence identity and similarity shown by human and non-human TIMPs compared to the human TIMP-4.

From: Tissue Inhibitor of Metalloproteinases-4. The road less traveled

Protein

Identity

(%)

Similarity

(%)

hTIMP-1

37

57

hTIMP-2

51

70

hTIMP-3

51

70

paTIMP-4

100

-

muTIMP-4

91

95

raTIMP-4

92

96

boTIMP-4

90

96

tkTIMP-4

55

73

drTIMP*

21

43

  1. The amino acid sequences analyzed are the same as shown in Fig. 1 and the analysis was performed with BioEdit (Hall, T.A., 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT.Nucl. Acids. Symp. Ser. 41:95–98).
  2. * Drosophila melanogaster TIMP (gi 4157982)