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Figure 1 | Molecular Cancer

Figure 1

From: Tissue Inhibitor of Metalloproteinases-4. The road less traveled

Figure 1

Comparison of the amino acid sequence of the human TIMP-4 (hTIMP-4) with those of the other human TIMPs (hTIMP-1, hTIMP-2, and hTIMP3) and TIMP-4 from Pan troglodytes (paTIMP-4) Mus musculus (muTIMP-4), Rattus norvegicus (raTIMP-4), Bos taurus (boTIMP-4), and Takifugus rubripes (tkTIMP-4). The residues that differ from those encoded by hTIMP-4 are indicated. The secondary structure elements are aligned with the amino acid sequence of the TIMPs and labeled (H and β mean "helix" and "β-strand", respectively). The following amino acid sequences were used in the alignment (The GenInfo Identifier numbers, gi, are shown in parentheses): hTIMP-1 (49456917), hTIMP-2 (4507511), hTIMP-3 (47678717), hTIMP-4 (3493223), paTIMP-4 (55619817), muTIMP-4 (110625888), raTIMP-4 (160370007), boTIMP-4 (109886638), tkTIMP-4 (29611415). The alignment was performed with ClustalX (Thompson, J.D., Gibson, T.J., Plewniak, F., Jeanmougin, F. and Higgins, D.G. 1997. The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Research, 24:4876–4882).

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